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A Comparison & Caution of the use of C13 Urea Breath
Tests (UBT)
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The Caution & the Difference in breathing into AP UBT "bags"
and "tubes" during UBT for the diagnosis of H. pylori
infection |
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We would strongly recommend our clients to use our AP UBT
"Bags" over "regular test Tubes" for UBT analysis under the
following important technical reasons : |
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To breathe
into our AP bag is to fill up exhale air (breath) from
zero volume to the full bag volume in the sealed air
tight bag.
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To breathe
into a tube is to exhale air (breath) to displace
existing air in the tube. It is a dilution, or rather, a
gradual concentration from the breath. There is still a
dilution effect there, depend on the breathe-in skill of
the patients.
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It is a
recommended method to do with bags, particularly for an
unsophisticated patient who does not master the exhaling
technique. The bag collects much larger volume of all
exhaled air and, enough to conduct few more times for
analysis if necessary.
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When a
patient exhales strongly into the tube, breathe-in air
could bounce out from the tube. Hence, the surrounding
air could suck into the tube to cause another dilution
of exhaled air collected. This dilution could cause
false negative results if tubes are used.
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When a
patient exhales into a regular test tube, moisture tends
to condense on tube wall. The layer of moisture will
allow some CO2 to dissolve in it. When the
diagnostic instrument withdraws air from the tube, less
CO2 will be drawn for analysis. Hence, it
could add to another factor of false negative result,
especially when the case is a boundary case.
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Therefore, "Using "Bag" instead of "Tube" will just avoid all
these mentioned problems and is the best tool for the
analysis" |
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Hence, summarize all the above five (5) points, it is easy
to come up false negative results. We strongly urge our
clients to use our" AP UBT bags".
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